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TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variants

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TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variantsKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2 type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

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Description

Several alternatively spliced transcript variants have been identified

In addition to its role in the metabolism of endogenous substances

high level in activated lymphocytes and monocytes

An important paralog of this gene is ACOT2

but they differ significantly over the 3' untranslated regions

TIEG-1/2 Polyclonal Antibody, 50ul Site-directed Mutagenesis Several alternatively spliced transcript variantsKLF10 (Kruppel like factor 10) encodes a member of a family of proteins that feature C2H2 type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

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