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While semaglutide effectively reduces appetite in most individuals, persistent hunger can occur due to insufficient dosing duration, hormonal adaptation, dietary factors, or individual variation in medication response

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High inflammation in tumors has been shown to be associated with increased survival in almost all cancer patients ( 3.1.4 Tumor-associated macrophages (TAMs) TAMs promote cancer growth and metastasis by secreting growth factors, cytokines, and proteases, and they also promote chronic inflammation by releasing mediators such as TNF, TGF-, IL-6, and IL-12

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