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Most reactions are transient and decrease in frequency with continued use as patients develop tolerance

It seems that the only common denominator is fasting for a certain period of time, alternating with a period of food intake

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Serrapeptase, nattokinase, N-acetylcysteine (NAC), and EDTA-based formulations degrade the biofilm scaffold, exposing the embedded yeast cells to antifungal agents that would otherwise be ineffective