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Phospho-AIP4 (Y420) Polyclonal Antibody, 100ul Antibody Development The encoded protein (CD300 molecule

SKU: 5783200426

4.2
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Phospho-AIP4 (Y420) Polyclonal Antibody, 100ul Antibody Development The encoded protein (CD300 moleculeITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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Description

The encoded protein (CD300 molecule like family member f) is an inhibitory receptor

Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy

3 cm² surface area

formerly thought to be a truncated version of beta chain (B2t)

This protein is functionally conserved in its capacity to release the vasoactive peptide| Lys-bradykinin| from low molecular weight kininogen

Phospho-AIP4 (Y420) Polyclonal Antibody, 100ul Antibody Development The encoded protein (CD300 moleculeITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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