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Whilst not everyone experiences sickness, it is sufficiently common that healthcare professionals routinely counsel patients about this possibility before starting treatment

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[DOI] [PubMed] [Google Scholar] [100].McClung JP, Roneker CA, Mu W, Lisk DJ, Langlais P, Liu F, Lei XG, Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase

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For instance, in SH-SY5Y neurons, 27-OHC activates the TGF-/NF-B signaling pathway, inducing TNFa production and iNOS expression, while suppressing IL-10 production (Ma et al., 2019)