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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes New England Journal of Medicine Research Summaries accompanying Original Articles in the April 9, 2026, issue of NEJM: ( ) Among patients Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes New England Journal of Medicine Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity New England Journal of Medicine In the SURMOUNT 5 phase 3b trial involving adults with obesity without type 2 diabetes, tirzepatide was superior to semaglutide in reducing body weight and waist circumference. Full trial results and Research Summary Frontiers Cardiovascular Safety and Benefits of Semaglutide in Patients With Type 2 Diabetes: Findings From SUSTAIN 6 and PIONEER 6
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