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Rare but Serious Considerations While generally well-tolerated, semaglutide carries important warnings that require medical attention: Pancreatitis: There's been concern about whether semaglutide increases the risk of pancreatitis (inflammation of the pancreas)

doi: 10.4103/0253-7613.132160 171 JuSGeYLiPTianXWangHZhengXet al

Insulin response scales with glucose, limiting hypoglycemia risk relative to non-incretin secretagogues

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These results are often more pronounced than those achieved through diet and exercise alone, especially in individuals who are obese or have been struggling with weight loss for a long time