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Psychological side effects Psychological side effects can be just as severe as physical ones and include: Aggression and mood changes: Steroids can cause significant changes in behavior, including increased aggression and irritability

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[1] How Prednisolone May Affect Weight Loss on Wegovy Prednisolone can significantly counteract the weight loss effects of Wegovy through several physiological mechanisms

This degradation is partially inhibited by bortezomib, suggesting a role for the ubiquitin-proteasome system, although only low levels of ubiquitination are detected