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Upon treatment with 2 mM NAC, cell death induced by the combination of 100 M BSO and 0.3 M DPI dropped from 98.34 0.44% to 25.79 12.99%, suggesting that an exogenous antioxidant supplement could largely attenuate the killing effect of the BSO and DPI combination (Fig

10.1016/j.cell.2018.08.041 Summary Keywords GLP-1, gut microbiota, microbiome, pancreatic -cells, probiotics, single-cell transcriptomics, type 2 diabetes Citation Ruchko E, Chernysheva M, Sokolov V, Starinnov Z, Sabirov M and Vasiliev A (2026) -cell heterogeneity and molecular plasticity in type 2 diabetes: multi-omics perspectives and the role of gut microbiota

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Inositol Inositol, a carbohydrate similar in structure to glucose, can have various roles in the body, including acting as a precursor for signaling molecules that influence insulin action [5]