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GLP-1-based therapies and resmetirom operate through distinct and potentially complementary mechanisms: while resmetirom exerts direct hepatic effects by activating THR- to enhance mitochondrial function, reduce hepatic lipogenesis, and promote lipid oxidation specifically in hepatocytes, GLP-1 RAs and multi-agonists address the upstream metabolic drivers of MASLD including insulin resistance, obesity, and systemic inflammation

Data were accessed through the secured All of Us Researcher Workbench, a cloud-based platform compliant with federal privacy and security standards (25)

Journal of Gastroenterology and Hepatology, 35(2), 80-85

& Fruehauf, J

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Choosing the Right Glutathione Supplement for You Glutathione does not easily get through the stomach intact, which means that the best form is not capsules or tablets that are swallowed