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People prefer the reduced form because it is the "active" version of the molecule

Mechanisms of treatment effects using allogeneic, umbilical cord-derived mesenchymal stromal stem cells (MSCs) in knee osteoarthritis: a pharmacological clinical study protocol

A tryptophan-deficient diet leads to more severe EAE, whereas tryptophan supplementation reverses this effect, suggesting that tryptophan metabolites exert their functions through activation of AhR in microglia