IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domains

Contains 10 EGF-like domains

In addition| using a separate promoter in an intron in the 3' region| it encodes telokin| a small protein identical in sequence to the C-terminus of myosin light chain kinase| that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments

tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver

It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid

and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domainsIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants